Epidemiological dynamics of an urban Dengue 4 outbreak in Sao Paulo, Brazil.

ABSTRACT:

Background

Dengue studies at the urban scale are scarce and required for guiding control efforts. In Brazil, the burden of dengue is high and challenges city public health administrations with limited resources. Here we studied the dynamics of a dengue epidemic in a single city.

Methods

Serum samples from dengue suspected cases were collected and tested, from December 2012 and July 2013 in Guarujá, Brazil. We use incidence series analysis to provide a detailed view of the reproduction number dynamics and a Bayesian analysis to infer the spread of the serotype using geographic and temporal data.

Results

We obtained nucleotide sequences from 354 envelope genes and georeferenced 286 samples during the course of the outbreak. Serotype 4 was responsible for the epidemic. W

SUBMITTER: Villabona-Arenas CJ 

PROVIDER: S-EPMC4824887 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature