Prenatal and postnatal stress and wheeze in Mexican children: Sex-specific differences.

ABSTRACT:

Background

Increasing evidence links early-life exposure to psychosocial stress with adverse childhood respiratory outcomes. The influence of exposure timing has not been completely elucidated.

Objective

To examine the association between prenatal and postnatal maternal stress and wheeze in 417 children enrolled in a prospective birth cohort in Mexico City.

Methods

Maternal negative life event (NLE) scores were ascertained in the second or third trimester of pregnancy and at the 48-month postnatal visit. Children's respiratory outcomes, caregiver report of ever wheeze, and wheeze in the past 12 months were obtained from the International Study of Asthma and Allergies in Childhood survey administered at 48 months. Associations between prenatal and postnatal NLE scores

SUBMITTER: Rosa MJ 

PROVIDER: S-EPMC4826313 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature