Sex differences in comorbidity at diagnosis of multiple sclerosis: A population-based study.

ABSTRACT:

Objective

To determine the prevalence of comorbidity in the multiple sclerosis (MS) population at the time of MS diagnosis. We also compared the prevalence of comorbidity in the MS population to that in a matched cohort from the general population.

Methods

Using population-based administrative health data from 4 Canadian provinces, we identified 23,382 incident MS cases and 116,638 age-, sex-, and geographically matched controls. We estimated the prevalence of hypertension, diabetes, hyperlipidemia, heart disease, chronic lung disease, epilepsy, fibromyalgia, inflammatory bowel disease, depression, anxiety, bipolar disorder, and schizophrenia at MS diagnosis using validated case definitions. We compared the populations using rate ratios.

Results

Of the MS cases, 16,80

SUBMITTER: Marrie RA 

PROVIDER: S-EPMC4826338 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature