Network dysfunction predicts speech production after left hemisphere stroke.

ABSTRACT:

Objective

To investigate the role of multiple distributed brain networks, including the default mode, fronto-temporo-parietal, and cingulo-opercular networks, which mediate domain-general and task-specific processes during speech production after aphasic stroke.

Methods

We conducted an observational functional MRI study to investigate the effects of a previous left hemisphere stroke on functional connectivity within and between distributed networks as patients described pictures. Study design included various baseline tasks, and we compared results to those of age-matched healthy participants performing the same tasks. We used independent component and psychophysiological interaction analyses.

Results

Although activity within individual networks was not predictive of

SUBMITTER: Geranmayeh F 

PROVIDER: S-EPMC4826341 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature