Dataset Information

Severe Acute Respiratory Illness Deaths in Sub-Saharan Africa and the Role of Influenza: A Case Series From 8 Countries.

ABSTRACT:

Background

Data on causes of death due to respiratory illness in Africa are limited.

Methods

From January to April 2013, 28 African countries were invited to participate in a review of severe acute respiratory illness (SARI)-associated deaths identified from influenza surveillance during 2009-2012.

Results

Twenty-three countries (82%) responded, 11 (48%) collect mortality data, and 8 provided data. Data were collected from 37 714 SARI cases, and 3091 (8.2%; range by country, 5.1%-25.9%) tested positive for influenza virus. There were 1073 deaths (2.8%; range by country, 0.1%-5.3%) reported, among which influenza virus was detected in 57 (5.3%). Case-fatality proportion (CFP) was higher among countries with systematic death reporting than among those with sporadic reporting. The influenza-associated CFP was 1.8% (57 of 3091), compared with 2.9% (1016 of 34 623) for influenza virus-negative cases (P < .001). Among 834 deaths (77.7%) tested for other respiratory pathogens, rhinovirus (107 [12.8%]), adenovirus (64 [6.0%]), respiratory syncytial virus (60 [5.6%]), and Streptococcus pneumoniae (57 [5.3%]) were most commonly identified. Among 1073 deaths, 402 (37.5%) involved people aged 0-4 years, 462 (43.1%) involved people aged 5-49 years, and 209 (19.5%) involved people aged ≥50 years.

Conclusions

Few African countries systematically collect data on outcomes of people hospitalized with respiratory illness. Stronger surveillance for deaths due to respiratory illness may identify risk groups for targeted vaccine use and other prevention strategies.

SUBMITTER: McMorrow ML

PROVIDER: S-EPMC4826902 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature

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Publications

Severe Acute Respiratory Illness Deaths in Sub-Saharan Africa and the Role of Influenza: A Case Series From 8 Countries.

McMorrow Meredith L ML Wemakoy Emile Okitolonda EO Tshilobo Joelle Kabamba JK Emukule Gideon O GO Mott Joshua A JA Njuguna Henry H Waiboci Lilian L Heraud Jean-Michel JM Rajatonirina Soatianana S Razanajatovo Norosoa H NH Chilombe Moses M Everett Dean D Heyderman Robert S RS Barakat Amal A Nyatanyi Thierry T Rukelibuga Joseph J Cohen Adam L AL Cohen Cheryl C Tempia Stefano S Thomas Juno J Venter Marietjie M Mwakapeje Elibariki E Mponela Marcelina M Lutwama Julius J Duque Jazmin J Lafond Kathryn K Nzussouo Ndahwouh Talla NT Williams Thelma T Widdowson Marc-Alain MA

The Journal of infectious diseases 20150223 6

<h4>Background</h4>Data on causes of death due to respiratory illness in Africa are limited.<h4>Methods</h4>From January to April 2013, 28 African countries were invited to participate in a review of severe acute respiratory illness (SARI)-associated deaths identified from influenza surveillance during 2009-2012.<h4>Results</h4>Twenty-three countries (82%) responded, 11 (48%) collect mortality data, and 8 provided data. Data were collected from 37 714 SARI cases, and 3091 (8.2%; range by country ...[more]

PMID: 25712970

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Dataset Information

Severe Acute Respiratory Illness Deaths in Sub-Saharan Africa and the Role of Influenza: A Case Series From 8 Countries.

Background

Methods

Results

Conclusions

Publications

Severe Acute Respiratory Illness Deaths in Sub-Saharan Africa and the Role of Influenza: A Case Series From 8 Countries.

Similar Datasets

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