Transcription factors in microalgae: genome-wide prediction and comparative analysis.

ABSTRACT:

Background

Studying transcription factors, which are some of the key players in gene expression, is of outstanding interest for the investigation of the evolutionary history of organisms through lineage-specific features. In this study we performed the first genome-wide TF identification and comparison between haptophytes and other algal lineages.

Results

For TF identification and classification, we created a comprehensive pipeline using a combination of BLAST, HMMER and InterProScan software. The accuracy evaluation of the pipeline shows its applicability for every alga, plant and cyanobacterium, with very good PPV and sensitivity. This pipeline allowed us to identify and classified the transcription factor complement of the three haptophytes Tisochrysis lutea, Emiliania hu

SUBMITTER: Thiriet-Rupert S 

PROVIDER: S-EPMC4827209 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature