Cognition in individuals at risk for Parkinson's: Parkinson associated risk syndrome (PARS) study findings.

ABSTRACT:

Objectives

The Parkinson Associated Risk Syndrome Study identified a cohort of healthy adults with hyposmia and dopamine transporter binding reduction to characterize individuals at risk for Parkinson's disease (PD). We describe the cognitive profile of this cohort.

Methods

Individuals older than 50 y without PD were recruited. Two hundred twenty-five completed cognitive testing and were included in the final analysis. A neuropsychological test battery was administered and normative scores created for global cognition, memory, executive function/working memory, processing speed/attention, visuospatial abilities, and language domains. Other non-motor symptoms (constipation, depression, anxiety, and rapid eye movement sleep behavior disorder) were assessed through questionnair

SUBMITTER: Chahine LM 

PROVIDER: S-EPMC4827252 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature