Sugar-sweetened beverage, diet soda, and fatty liver disease in the Framingham Heart Study cohorts.

ABSTRACT:

Background & aims

Non-alcoholic fatty liver disease affects ∼30% of US adults, yet the role of sugar-sweetened beverages and diet soda on these diseases remains unknown. We examined the cross-sectional association between intake of sugar-sweetened beverages or diet soda and fatty liver disease in participants of the Framingham Offspring and Third Generation cohorts.

Methods

Fatty liver disease was defined using liver attenuation measurements generated from computed tomography in 2634 participants. Alanine transaminase concentration, a crude marker of fatty liver disease, was measured in 5908 participants. Sugar-sweetened beverage and diet soda intake were estimated using a food frequency questionnaire. Participants were categorized as either non-consumers or consumers (3 cat

SUBMITTER: Ma J 

PROVIDER: S-EPMC4827616 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature