MR Imaging Characteristics of Wingless-Type-Subgroup Pediatric Medulloblastoma.

ABSTRACT:

Background and purpose

"Transcriptionally different" medulloblastoma groups are associated with specific signaling pathway abnormalities; hence, they may present with distinct imaging manifestations. In this study, we sought to describe the MR imaging features of wingless-type-subgroup medulloblastomas with embryologic correlations.

Materials and methods

Pre- and postoperative imaging studies of 16 patients with wingless-type-subgroup medulloblastoma were evaluated for tumor location, involvement of surrounding CSF spaces or parenchymal structures, conventional and DWI signal properties, and postsurgical damage patterns. Laterality scores were assigned to tumors at each step in the evaluation process. Continuous variables were summarized by using descriptive statistics. The

SUBMITTER: Patay Z 

PROVIDER: S-EPMC4827780 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature