Common Genetic Variants in FOXP2 Are Not Associated with Individual Differences in Language Development.

ABSTRACT: Much of our current knowledge regarding the association of FOXP2 with speech and language development comes from singleton and small family studies where a small number of rare variants have been identified. However, neither genome-wide nor gene-specific studies have provided evidence that common polymorphisms in the gene contribute to individual differences in language development in the general population. One explanation for this inconsistency is that previous studies have been limited to relatively small samples of individuals with low language abilities, using low density gene coverage. The current study examined the association between common variants in FOXP2 and a quantitative measure of language ability in a population-based cohort of European decent (n = 812). No significant asso

SUBMITTER: Mueller KL 

PROVIDER: S-EPMC4827837 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature