Therapeutic Outcomes and Prognostic Factors in Childhood Absence Epilepsy.

ABSTRACT:

Background and purpose

Childhood absence epilepsy (CAE) is one of the most common types of pediatric epilepsy. It is generally treated with ethosuximide (ESM), valproic acid (VPA), or lamotrigine (LTG), but the efficacy and adverse effects of these drugs remain controversial. This study compared initial therapy treatment outcomes, including VPA-LTG combination, and assessed clinical factors that may predict treatment response and prognosis.

Methods

Sixty-seven patients with typical CAE were retrospectively enrolled at the Korea University Medical Center. We reviewed patients' clinical characteristics, including age of seizure onset, seizure-free interval, duration of seizure-free period, freedom from treatment failure, breakthrough seizures frequency, and electroencephalogra

SUBMITTER: Kim HR 

PROVIDER: S-EPMC4828561 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature