Frequency of spontaneous BOLD signal shifts during infancy and correlates with cognitive performance.

ABSTRACT: Numerous studies have been conducted to delineate the early development of different functional networks, based on measuring the temporal synchronization of spontaneous blood oxygenation level-dependent (BOLD) signals acquired using resting state functional MRI (rsfMRI). However, little attention has been paid to the change of the frequency properties of these signals during early brain development. Such frequency properties may reflect important physiological changes and potentially have significant cognitive consequences. In this study, leveraging a large (N=86 subjects), longitudinal sample of human infants scanned during the first two years of life, we aimed to specifically delineate the developmental changes of the frequency characteristics of spontaneous BOLD signals. Both whole-brai

SUBMITTER: Alcauter S 

PROVIDER: S-EPMC4830279 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature