Predictive models to estimate utility from clinical questionnaires in schizophrenia: findings from EuroSC.

ABSTRACT:

Objective

The clinical symptoms of schizophrenia are associated with serious social, quality of life and functioning alterations. Typically, data on health utilities are not available in clinical studies in schizophrenia. This makes the economic evaluation of schizophrenia treatments challenging. The purpose of this article was to provide a mapping function to predict unobserved utility values in patients with schizophrenia from the available clinical and socio-demographic information.

Methods

The analysis was performed using data from EuroSC, a 2-year, multi-centre, cohort study conducted in France (N = 288), Germany (N = 618), and the UK (N = 302), totalling 1208 patients. Utility was calculated based on the EQ-5D questionnaire. The relationships between the utility values

SUBMITTER: Siani C 

PROVIDER: S-EPMC4830865 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature