A case-control study of dietary salt intake in pediatric-onset multiple sclerosis.

ABSTRACT:

Background

High salt intake may be associated with pro-inflammatory changes in the immune response, and increased clinical and MRI activity in adults with relapsing-remitting multiple sclerosis.

Objective

We sought to determine if dietary salt intake is associated with pediatric-onset MS risk in a multicenter, case-control study.

Methods

Pediatric-onset CIS/MS cases within four years of onset and controls less than 22 years old recruited from 14 pediatric-MS centers were studied. Dietary sodium intake was assessed using the validated Block Kids Food Screener (NutritionQuest). Sodium intake, excess sodium, and sodium terciles were compared between cases and controls. Logistic regression models were adjusted for age, gender, ethnicity, body mass index, and socioeconomic

SUBMITTER: McDonald J 

PROVIDER: S-EPMC4830915 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature