Ontology highlight
ABSTRACT:
SUBMITTER: Zhu WS
PROVIDER: S-EPMC4830926 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Zhu Wen Si WS Guo Wei W Zhu Jie Ning JN Tang Chun Mei CM Fu Yong Heng YH Lin Qiu Xiong QX Tan Ning N Shan Zhi Xin ZX
Scientific reports 20160414
The role of microRNA-1 (miR-1) in ischemia/reperfusion (I/R)-induced injury is not well illustrated. The present study aimed to investigate the expression and potential target of miR-1 in the myocardium of a rat model of I/R. The apoptosis of cardiomyocytes in the ischemic rat myocardium increased on day 1, then attenuated on day 3 and day 7 post-I/R. Heat shot protein 90 (Hsp90) aa1 mRNA expression was decreased post-I/R, and Hsp90aa1 protein level was decreased on day1 post-I/R, but was revers ...[more]