Recommendations for observational studies of comorbidity in multiple sclerosis.

ABSTRACT:

Objective

To reach consensus about the most relevant comorbidities to study in multiple sclerosis (MS) with respect to incidence, prevalence, and effect on outcomes; review datasets that may support studies of comorbidity in MS; and identify MS outcomes that should be prioritized in such studies.

Methods

We held an international workshop to meet these objectives, informed by a systematic review of the incidence and prevalence of comorbidity in MS, and an international survey regarding research priorities for comorbidity.

Results

We recommend establishing age- and sex-specific incidence and prevalence estimates for 5 comorbidities (depression, anxiety, hypertension, hyperlipidemia, and diabetes); evaluating the effect of 7 comorbidities (depression, anxiety, hypertensi

SUBMITTER: Marrie RA 

PROVIDER: S-EPMC4831039 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature