Birth weight and asthma incidence by asthma phenotype pattern in a racially diverse cohort followed through adolescence.

ABSTRACT:

Objective

Low birth weight (LBW) has been shown to be an independent risk factor for asthma. We hypothesized that LBW would have its greatest impact on early onset disease.

Methods

A racially diverse cohort of children born from 1983 to 1985 at two hospitals, one urban and one suburban in the same metropolitan area, and oversampled for babies weighing ≤2500 g, was identified retrospectively when the children were 6 years of age and followed periodically. At the age 17 years study visit, cohort members and their parent/guardians were separately interviewed face-to-face regarding the subject's history of asthma using the standardized ISAAC questionnaire. We measured the cumulative incidence of asthma from birth through adolescence defined by age of diagnosis and persistence/re

SUBMITTER: Johnson CC 

PROVIDER: S-EPMC4831062 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature