Emerging pan-resistance in Trichosporon species: a case report.

ABSTRACT:

Background

Trichosporon species are ubiquitously spread and known to be part of the normal human flora of the skin and gastrointestinal tract. Trichosporon spp. normally cause superficial infections. However, in the past decade Trichosporon spp. are emerging as opportunistic agents of invasive fungal infections, particularly in severely immunocompromised patients. Clinical isolates are usually sensitive to triazoles, but strains resistant to multiple triazoles have been reported.

Case presentation

We report a high-level pan-azole resistant Trichosporon dermatis isolate causing an invasive cholangitis in a patient after liver re-transplantation. This infection occurred despite of fluconazole and low dose amphotericin B prophylaxis, and treatment with combined liposomal amphot

SUBMITTER: Oliveira dos Santos C 

PROVIDER: S-EPMC4831108 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature