ACTN3 R577X and ACE I/D gene variants influence performance in elite sprinters: a multi-cohort study.

ABSTRACT:

Background

To date, studies investigating the association between ACTN3 R577X and ACE I/D gene variants and elite sprint/power performance have been limited by small cohorts from mixed sport disciplines, without quantitative measures of performance.

Aim

To examine the association between these variants and sprint time in elite athletes.

Methods

We collected a total of 555 best personal 100-, 200-, and 400-m times of 346 elite sprinters in a large cohort of elite Caucasian or African origin sprinters from 10 different countries. Sprinters were genotyped for ACTN3 R577X and ACE ID variants.

Results

On average, male Caucasian sprinters with the ACTN3 577RR or the ACE DD genotype had faster best 200-m sprint time than their 577XX (21.19 ± 0.53 s vs. 21.86 ± 0.54 s,

SUBMITTER: Papadimitriou ID 

PROVIDER: S-EPMC4831144 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature