Development of a Short Version of MSQOL-54 Using Factor Analysis and Item Response Theory.

ABSTRACT:

Background

The Multiple Sclerosis Quality of Life-54 (MSQOL-54, 52 items grouped in 12 subscales plus two single items) is the most used MS specific health related quality of life inventory.

Objective

To develop a shortened version of the MSQOL-54.

Methods

MSQOL-54 dimensionality and metric properties were investigated by confirmatory factor analysis (CFA) and Rasch modelling (Partial Credit Model, PCM) on MSQOL-54s completed by 473 MS patients. Their mean age was 41 years, 65% were women, and median Expanded Disability Status Scale (EDSS) score was 2.0 (range 0-9.5). Differential item functioning (DIF) was evaluated for gender, age and EDSS. Dimensionality of the resulting short version was assessed by exploratory factor analysis (EFA) and CFA. Cognitive debriefing o

SUBMITTER: Rosato R 

PROVIDER: S-EPMC4831784 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature