Cholesterol as a Risk Factor for Subarachnoid Hemorrhage: A Systematic Review.

ABSTRACT:

Background

The role played by total cholesterol (TC) in risk for subarachnoid hemorrhage (SAH) is unclear because studies report both high and low TC each as a risk factor. We performed a systematic review to clarify associations between lipid profile and SAH.

Methods

Our literature search comprised Pubmed, Scopus, and Cochrane Library databases with no language, publication year, or study type limitations. The Preferred Reporting Items for Systematic reviews and Meta-analyses (PRISMA) checklist guided our reporting. Data forms adapted from the Critical Appraisal Skills Program (CASP), and Cochrane Collaboration guidelines provided a platform for risk-of-bias evaluation. We used a random effects model to calculate pooled estimates and assessed heterogeneity with I2-statistic

SUBMITTER: Lindbohm JV 

PROVIDER: S-EPMC4831795 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature