Mapping human preictal and ictal haemodynamic networks using simultaneous intracranial EEG-fMRI.

ABSTRACT: Accurately characterising the brain networks involved in seizure activity may have important implications for our understanding of epilepsy. Intracranial EEG-fMRI can be used to capture focal epileptic events in humans with exquisite electrophysiological sensitivity and allows for identification of brain structures involved in this phenomenon over the entire brain. We investigated ictal BOLD networks using the simultaneous intracranial EEG-fMRI (icEEG-fMRI) in a 30 year-old male undergoing invasive presurgical evaluation with bilateral depth electrode implantations in amygdalae and hippocampi for refractory temporal lobe epilepsy. One spontaneous focal electrographic seizure was recorded. The aims of the data analysis were firstly to map BOLD changes related to the ictal activity identifie

SUBMITTER: Chaudhary UJ 

PROVIDER: S-EPMC4832091 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature