The Burden of Typhoid and Paratyphoid in India: Systematic Review and Meta-analysis.

ABSTRACT:

Background

Typhoid is an important public health challenge for India, especially with the spread of antimicrobial resistance. The decision about whether to introduce a public vaccination programme needs to be based on an understanding of disease burden and the age-groups and geographic areas at risk.

Methods

We searched Medline and Web of Science databases for studies reporting the incidence or prevalence of typhoid and paratyphoid fever confirmed by culture and/or serology, conducted in India and published between 1950 and 2015. We used binomial and Poisson mixed-effects meta-regression models to estimate prevalence and incidence from hospital and community studies, and to identify risk-factors.

Results

We identified 791 titles and abstracts, and included 37 studies

SUBMITTER: John J 

PROVIDER: S-EPMC4833325 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature