Concordance Between BeamF3 and MRI-neuronavigated Target Sites for Repetitive Transcranial Magnetic Stimulation of the Left Dorsolateral Prefrontal Cortex.

ABSTRACT:

Background

The dorsolateral prefrontal cortex (DLPFC) is a common target for repetitive transcranial magnetic stimulation (rTMS) in major depression, but the conventional "5 cm rule" misses DLPFC in >1/3 cases. Another heuristic, BeamF3, locates the F3 EEG site from scalp measurements. MRI-guided neuronavigation is more onerous, but can target a specific DLPFC stereotaxic coordinate directly. The concordance between these two approaches has not previously been assessed.

Objective

To quantify the discrepancy in scalp site between BeamF3 versus MRI-guided neuronavigation for left DLPFC.

Methods

Using 100 pre-treatment MRIs from subjects undergoing left DLPFC-rTMS, we localized the scalp site at minimum Euclidean distance from a target MNI coordinate (X - 38 Y + 44 Z + 2

SUBMITTER: Mir-Moghtadaei A 

PROVIDER: S-EPMC4833442 | biostudies-literature | 2015 Sep-Oct

REPOSITORIES: biostudies-literature