Vitamin D deficiency as adverse drug reaction? A cross-sectional study in Dutch geriatric outpatients.

ABSTRACT:

Purpose

Adverse drug reactions as well as vitamin D deficiency are issues of public health concern in older people. However, relatively little is known about the impact of drug use on vitamin D status. Our primary aim is to explore associations between drug use and vitamin D status in older people. Furthermore, prevalences of drug use and vitamin D deficiency are estimated.

Methods

In a population of 873 community-dwelling Dutch geriatric outpatients, we explored the cross-sectional relationships of polypharmacy (≥5 medications concomitantly used), severe polypharmacy (≥10 medications), and use of twenty-one specific drug groups, with serum 25-hydroxyvitamin D (25(OH)D) by analysis of covariance.

Results

Overall prevalence of polypharmacy was 65 %, of severe polypharm

SUBMITTER: van Orten-Luiten AC 

PROVIDER: S-EPMC4834096 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature