Endovascular treatment versus medical care alone for ischaemic stroke: systematic review and meta-analysis.

ABSTRACT:

Objectives

To evaluate the efficacy and safety of endovascular treatment, particularly adjunctive intra-arterial mechanical thrombectomy, in patients with ischaemic stroke.

Design

Systematic review and meta-analysis.

Data sources

Medline, Embase, Cochrane Central Register of Controlled Trials, Web of Science, SciELO, LILACS, and clinical trial registries from inception to December 2015. Reference lists were crosschecked.

Eligibility criteria for selecting studies

Randomised controlled trials in adults aged 18 or more with ischaemic stroke comparing endovascular treatment, including thrombectomy, with medical care alone, including intravenous recombinant tissue plasminogen activator (rt-PA). Trial endpoints were functional outcome (modified Rankin scale scores o

SUBMITTER: Rodrigues FB 

PROVIDER: S-EPMC4834754 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature