Current Status and Perspectives in Stem Cell Therapy for Heart.

ABSTRACT:

Unlabelled

For most patients, the prognosis of heart failure remains poor despite therapeutic advancement in recent decades. The option of cardiac transplantation is high risk and limited by a shortage of donors. Traditionally, the heart had been considered a terminally differentiated organ incapable of regeneration. However, numerous preclinical and clinical studies have been performed since the first report of cell therapy in heart failure using skeletal myoblasts in 2001. These investigations looked at the promising potential and use of several kinds of stem cells, which could some day dramatically alter the understanding of the regenerative capacity of the heart. To date, although there is no existing cardiac cell therapy that has been conclusively reported to be effective, ste

SUBMITTER: Lin FC 

PROVIDER: S-EPMC4834955 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature