Wake High-Density Electroencephalographic Spatiospectral Signatures of Insomnia.

ABSTRACT:

Study objectives

Although daytime complaints are a defining characteristic of insomnia, most EEG studies evaluated sleep only. We used high-density electroencephalography to investigate wake resting state oscillations characteristic of insomnia disorder (ID) at a fine-grained spatiospectral resolution.

Methods

A case-control assessment during eyes open (EO) and eyes closed (EC) was performed in a laboratory for human physiology. Participants (n = 94, 74 female, 21-70 y) were recruited through www.sleepregistry.nl: 51 with ID, according to DSM-5 and 43 matched controls. Exclusion criteria were any somatic, neurological or psychiatric condition. Group differences in the spectral power topographies across multiple frequencies (1.5 to 40 Hz) were evaluated using permutation-base

SUBMITTER: Colombo MA 

PROVIDER: S-EPMC4835299 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature