OnabotulinumtoxinA and AbobotulinumtoxinA Dose Conversion: a Systematic Literature Review.

ABSTRACT:

Objective

This systematic review was performed to elucidate dosing practices, dosing conversions, and related outcomes from randomized controlled trials that directly compared onabotulinumtoxinA (ONA) and abobotulinumtoxinA (ABO) at various dose conversion ratios for therapeutic use in movement disorders.

Methods

A systematic review of 3 medical literature databases (PubMed, the Cochrane Library, and EMBASE) was performed to identify relevant comparative clinical studies, systematic reviews, and meta-analyses published in the English language between January 1991 and January 2015. Studies that met predefined inclusion criteria were selected for formal data extraction and quality assessment.

Results

A total of 182 manuscripts were identified, of which 4 were included f

SUBMITTER: Dashtipour K 

PROVIDER: S-EPMC4836618 | biostudies-literature | 2016 Mar-Apr

REPOSITORIES: biostudies-literature