Adipokines and Migraine: A Systematic Review.

ABSTRACT:

Background

Migraine is comorbid with obesity. Recent research suggests an association between migraine and adipocytokines, proteins that are predominantly secreted from adipose tissue and which participate in energy homeostasis and inflammatory processes.

Objectives

In this review, we first briefly discuss the association between migraine and obesity and the importance of adipose tissue as a neuroendocrine organ. We then present a systematic review of the extant literature evaluating circulating levels of adiponectin and leptin in those with migraine.

Methods

A search of the PubMed database was conducted using the keywords "migraine," "adiponectin," and "leptin." In addition reference lists of relevant articles were reviewed for possible inclusion. English language st

SUBMITTER: Peterlin BL 

PROVIDER: S-EPMC4836978 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature