Lung cancer prognosis before and after recurrence in a population-based setting.

ABSTRACT:

Background

Population-based estimates of absolute risk of lung cancer recurrence, and of mortality rates after recurrence, can inform clinical management.

Methods

We evaluated prognostic factors for recurrences and survival in 2098 lung cancer case patients from the general population of Lombardy, Italy, from 2002 to 2005. We conducted survival analyses and estimated absolute risks separately for stage IA to IIIA surgically treated and stage IIIB to IV non-surgically treated patients.

Results

Absolute risk of metastases exceeded that of local recurrence in every stage and cell type, highlighting the systemic threat of lung cancer. In stage I, the probability of dying within the first year after diagnosis was 2.7%, but it was 48.3% within first year after recurrence; i

SUBMITTER: Consonni D 

PROVIDER: S-EPMC4838060 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature