US assessment of HPV types in cancers: implications for current and 9-valent HPV vaccines.

ABSTRACT:

Background

This study sought to determine the prevaccine type-specific prevalence of human papillomavirus (HPV)-associated cancers in the United States to evaluate the potential impact of the HPV types in the current and newly approved 9-valent HPV vaccines.

Methods

The Centers for Disease Control and Prevention partnered with seven US population-based cancer registries to obtain archival tissue for cancers diagnosed from 1993 to 2005. HPV testing was performed on 2670 case patients that were fairly representative of all participating cancer registry cases by age and sex. Demographic and clinical data were evaluated by anatomic site and HPV status. Current US cancer registry data and the detection of HPV types were used to estimate the number of cancers potentially preventab

SUBMITTER: Saraiya M 

PROVIDER: S-EPMC4838063 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature