The Core Brain Region for Face Processing in Schizophrenia Lacks Face Selectivity.

ABSTRACT:

Background

Face perception impairment in schizophrenia has long been recognized. However, brain mechanisms underlying this socially important perceptual deficit are not well understood. Previous magnetic resonance imaging (MRI) studies have shown that patients have altered structure in brain regions responsible for processing face information, but functional properties of these brain regions are not clearly determined. A key functional property of the face-processing system--face selectivity--has yet to be evaluated in schizophrenia.

Methods

We used functional MRI (fMRI) to examine face selectivity of 3 core face-processing regions--fusiform face area (FFA), occipital face area (OFA), and superior temporal sulcus (STS)--in schizophrenia patients (n = 24) and healthy controls

SUBMITTER: Maher S 

PROVIDER: S-EPMC4838078 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature