Children and young adults with CF in the USA have better lung function compared with the UK.

ABSTRACT:

Background

People with cystic fibrosis (CF) are managed differently in the USA and UK providing an opportunity to learn from differences in practice patterns.

Objectives

To compare cross-sectional demographics, practice patterns and clinical outcomes between US and UK CF patients.

Methods

This was a cross-sectional study using 2010 data from patients in the US Cystic Fibrosis Foundation and the UK Cystic Fibrosis patient registries. The a priori outcome measures of interest were lung function and nutritional status. Descriptive statistics and two sample comparisons were performed. Stratification and multivariable linear regression were used to adjust for confounding.

Results

The study cohort included 13 777 children and 11 058 adults from the USA and 3968 child

SUBMITTER: Goss CH 

PROVIDER: S-EPMC4838510 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature