FeSe₂-Decorated Bi₂Se₃ Nanosheets Fabricated via Cation Exchange for Chelator-Free ⁶⁴Cu-labeling and Multimodal Image-Guided Photothermal-Radiation Therapy.

ABSTRACT: Multifunctional theranostic agents have become rather attractive to realize image-guided combination cancer therapy. Herein, we develop a novel method to synthesize Bi₂Se₃ nanosheets decorated with mono-dispersed FeSe₂ nanoparticles (FeSe₂/Bi₂Se₃) for tetra-modal image-guided combined photothermal & radiation tumor therapy. Interestingly, upon addition of Bi(NO₃)₃, pre-made FeSe₂ nanoparticles via cation exchange would be gradually converted into Bi₂Se₃ nanosheets, on which remaining FeSe₂ nanoparticles are decorated. The yielded FeSe₂/Bi₂Se₃ composite-nanostructures were then modified with polyethylene glycol (PEG). Taking adv

SUBMITTER: Cheng L 

PROVIDER: S-EPMC4838545 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature