Nine-Year Effects of 3.7 Years of Intensive Glycemic Control on Cardiovascular Outcomes.

ABSTRACT:

Objective

In the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, ∼4 years of intensive versus standard glycemic control in participants with type 2 diabetes and other cardiovascular risk factors had a neutral effect on the composite cardiovascular outcome, increased cardiovascular and total mortality, and reduced nonfatal myocardial infarction. Effects of the intervention during prolonged follow-up were analyzed.

Research design and methods

All surviving ACCORD participants were invited to participate in the ACCORD Follow-on (ACCORDION) study, during which participants were treated according to their health care provider's judgment. Cardiovascular and other health-related outcomes were prospectively collected and analyzed using an intention-to-treat approac

SUBMITTER: ACCORD Study Group 

PROVIDER: S-EPMC4839177 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature