The influence of a short-term gluten-free diet on the human gut microbiome.

ABSTRACT:

Background

A gluten-free diet (GFD) is the most commonly adopted special diet worldwide. It is an effective treatment for coeliac disease and is also often followed by individuals to alleviate gastrointestinal complaints. It is known there is an important link between diet and the gut microbiome, but it is largely unknown how a switch to a GFD affects the human gut microbiome.

Methods

We studied changes in the gut microbiomes of 21 healthy volunteers who followed a GFD for four weeks. We collected nine stool samples from each participant: one at baseline, four during the GFD period, and four when they returned to their habitual diet (HD), making a total of 189 samples. We determined microbiome profiles using 16S rRNA sequencing and then processed the samples for taxonomic an

SUBMITTER: Bonder MJ 

PROVIDER: S-EPMC4841035 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature