Neighborhood socioeconomic status during childhood versus puberty in relation to endogenous sex hormone levels in adult women.

ABSTRACT:

Background

Socioeconomic adversity in early life is related to cardiovascular risk in adulthood; however, no studies have examined whether such adversity may be related to endogenous sex hormones, which are themselves associated with cardiovascular outcomes, or whether the timing of adversity exposures (childhood vs. puberty) matters.

Objective

The goal of the current study was to separately examine neighborhood socioeconomic status (SES) during periods of childhood and puberty in relation to adulthood levels of endogenous sex hormones (estradiol [E2], testosterone), sex hormone binding globulin (SHBG), and a derived index of bioavailable testosterone (free androgen index).

Methods

In a sample of 143 premenopausal women (mean age = 36.8 [SD = 5.5]; 51.7% White, 32.2%

SUBMITTER: Bleil ME 

PROVIDER: S-EPMC4841463 | biostudies-literature | 2015 May-Jun

REPOSITORIES: biostudies-literature