Dual Trajectories of Depression and Cognition: A Longitudinal Population-Based Study.

ABSTRACT:

Objective

To examine the relationships over time between dual trajectories of depressive symptoms and several cognitive domains.

Methods

In a 5-year longitudinal study, 1,978 randomly selected individuals aged 65+ years at recruitment were assessed annually. Repeated measures were of depressive symptoms on the modified Center for Epidemiologic Studies Depression Scale and composite scores in the cognitive domains of attention, executive function, memory, language, and visuospatial function. Latent class trajectories were identified for depression and for each cognitive domain and their associations investigated using dual trajectory modeling. Cognitive trajectories with z scores below -1 were designated as persistently low.

Results

Five depressive symptom trajectories

SUBMITTER: Graziane JA 

PROVIDER: S-EPMC4841743 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature