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Predictors of very low adherence with medications for osteoporosis: towards development of a clinical prediction rule.


ABSTRACT:

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We developed a clinical prediction rule score to predict medication non-adherence for women prescribed osteoporosis treatment. When combined into a summative score, 62% with seven or more points on the score demonstrated very low adherence. This compares with 17% subjects with fewer than seven points (c-statistic = 0.74).

Introduction

Medication non-adherence is extremely common for osteoporosis; however, no clear methods exist for identifying patients at risk of this behavior. We developed a clinical prediction rule to predict medication non-adherence for women prescribed osteoporosis treatment.

Methods

Women undergoing bone mineral density testing and fulfilling WHO criteria for osteoporosis were invited to complete a questionnaire and then followed for 1

SUBMITTER: Solomon DH 

PROVIDER: S-EPMC4843120 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature