From data repositories to submission portals: rethinking the role of domain-specific databases in CollecTF.

ABSTRACT: Domain-specific databases are essential resources for the biomedical community, leveraging expert knowledge to curate published literature and provide access to referenced data and knowledge. The limited scope of these databases, however, poses important challenges on their infrastructure, visibility, funding and usefulness to the broader scientific community. CollecTF is a community-oriented database documenting experimentally validated transcription factor (TF)-binding sites in the Bacteria domain. In its quest to become a community resource for the annotation of transcriptional regulatory elements in bacterial genomes, CollecTF aims to move away from the conventional data-repository paradigm of domain-specific databases. Through the adoption of well-established ontologies, identifiers a

SUBMITTER: Kılıc S 

PROVIDER: S-EPMC4843526 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature