Do Biliary Complications after Hypofractionated Radiation Therapy in Hepatocellular Carcinoma Matter?

ABSTRACT:

Purpose

The purpose of this study is to evaluate the efficacy of hypofractionated radiation therapy (RT) in the treatment of unresectable hepatocellular carcinoma (HCC) after failure of transarterial chemoembolization (TACE) or in cases of refractory HCC, and to investigate biliary complications after hypofractionated RT.

Materials and methods

We retrospectively enrolled patients with unresectable, TACE-unresponsive, or refractory HCC treated with hypofractionated RT between July 2006 and December 2012. The perihilar region was defined as the 1-cm area surrounding the right, left, and the common hepatic duct, including the gallbladder and the cystic duct. Significant elevation of total bilirubin was defined as an increase of more than 3.0 mg/dL, and more than two times that

SUBMITTER: Yu JI 

PROVIDER: S-EPMC4843719 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature