Identification of Risk Factors for Mortality and Poor-Quality-of-Life Survival in Frail Older Women Participating in the Women's Health Initiative Observational Study.

ABSTRACT:

Objectives

To identify potentially modifiable factors associated with overall and poor-quality-of-life (QoL) survival in physically frail older women.

Design

Prospective study with 7 years of follow-up to examine mortality and, in survivors with a QoL measurement within the next 3 years, to examine poor- versus good-QoL patterns of survival.

Setting

Women's Health Initiative Observational Study (WHI OS).

Participants

Frail older women (N = 11,070; average age 72.6, range 65-82).

Measurements

Frailty was defined using the modified Fried criteria. Study outcomes were overall survival and global QoL. Risk factors were measured at the first follow-up clinic visit for WHI OS participants between 1997 and 2001.

Results

Of 11,070 frail women, 1,487 (13%)

SUBMITTER: Zaslavsky O 

PROVIDER: S-EPMC4843841 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature