Elastic Anisotropy of Trabecular Bone in the Elderly Human Vertebra.

ABSTRACT: Knowledge of the nature of the elastic symmetry of trabecular bone is fundamental to the study of bone adaptation and failure. Previous studies have classified human vertebral trabecular bone as orthotropic or transversely isotropic but have typically obtained samples from only selected regions of the centrum. In this study, the elastic symmetry of human vertebral trabecular bone was characterized using microfinite element (μFE) analyses performed on 1019 cubic regions of side length equal to 5 mm, obtained via thorough sampling of the centrums of 18 human L1 vertebrae (age = 81.17 ± 7.7 yr; eight males and ten females). An optimization procedure was used to find the closest orthotropic representation of the resulting stiffness tensor for each cube. The orthotropic elastic constants and or

SUBMITTER: Unnikrishnan GU 

PROVIDER: S-EPMC4844108 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature