A meta-analysis of MMP-9 promoter -1562 C/T polymorphism on susceptibility of chronic periodontitis.

ABSTRACT:

Background

Although many studies have focused on the association of the MMP-9 promoter -1562 C/T polymorphism with the susceptibility and/or severity of chronic periodontitis (CP), results have been inconsistent. Therefore, a meta-analysis of all eligible studies was performed to derive a more precise estimation of the association between this polymorphism and CP risk.

Methods

All relevant studies were identified through a database search in PubMed, Medline, and Web of Science. All the full-text studies with appropriate analytical design, published in English, which evaluated the association of MMP-9 promoter -1562C/T polymorphism with CP risk using validated genotyping methods, and with non-duplicated data were selected for this study. A fixed-effect model was used to calcu

SUBMITTER: Ajmera DH 

PROVIDER: S-EPMC4844584 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature