Maturation of auditory neural processes in autism spectrum disorder - A longitudinal MEG study.

ABSTRACT:

Background

Individuals with autism spectrum disorder (ASD) show atypical brain activity, perhaps due to delayed maturation. Previous studies examining the maturation of auditory electrophysiological activity have been limited due to their use of cross-sectional designs. The present study took a first step in examining magnetoencephalography (MEG) evidence of abnormal auditory response maturation in ASD via the use of a longitudinal design.

Methods

Initially recruited for a previous study, 27 children with ASD and nine typically developing (TD) children, aged 6- to 11-years-old, were re-recruited two to five years later. At both timepoints, MEG data were obtained while participants passively listened to sinusoidal pure-tones. Bilateral primary/secondary auditory cortex time d

SUBMITTER: Port RG 

PROVIDER: S-EPMC4844592 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature