Capsular Typing Method for Streptococcus agalactiae Using Whole-Genome Sequence Data.

ABSTRACT: Group B streptococcus (GBS) capsular serotypes are major determinants of virulence and affect potential vaccine coverage. Here we report a whole-genome-sequencing-based method for GBS serotype assignment. This method shows strong agreement (kappa of 0.92) with conventional methods and increased serotype assignment (100%) to all 10 capsular types.

SUBMITTER: Sheppard AE 

PROVIDER: S-EPMC4844738 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature