Impact of antenatal steroids on intraventricular hemorrhage in very-low-birth weight infants.

ABSTRACT:

Objective

To determine the association between antenatal steroids administration and intraventricular hemorrhage rates.

Methods

We used cross-sectional data from the California Perinatal Quality Care Collaborative during 2007 to 2013 for infants ⩽32 weeks gestational age. Using multivariable logistic regression, we evaluated the effect of antenatal steroids on intraventricular hemorrhage, stratified by gestational age.

Results

In 25 979 very-low-birth weight infants, antenatal steroid use was associated with a reduction in incidence of any grade of intraventricular hemorrhage (odds ratio=0.68, 95% confidence interval: 0.62, 0.75) and a reduction in incidence of severe intraventricular hemorrhage (odds ratio=0.51, 95% confidence interval: 0.45, 0.58). This association

SUBMITTER: Wei JC 

PROVIDER: S-EPMC4844862 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature