Providing Rapid Out of Hospital Acute Cardiovascular Treatment 4 (PROACT-4).

ABSTRACT:

Background

Whether prehospital point-of-care (POC) troponin further accelerates the time to diagnosis in patients with chest pain (CP) is unknown. We conducted a randomized trial of POC-Troponin testing in the ambulance.

Methods and results

Patients with chest pain presenting by ambulance were randomized to usual care (UC) or POC-Troponin; ST-elevation myocardial infarction patients or those with noncardiovascular symptoms were excluded. Pre-hospital high-sensitivity troponin was analyzed on a POC device and available to the paramedic and emergency department (ED) staff. The final diagnosis was centrally adjudicated. The primary endpoint was time from first medical contact to discharge from ED or admission to hospital. We randomized 601 patients in 19 months; 296 to UC and 3

SUBMITTER: Ezekowitz JA 

PROVIDER: S-EPMC4845257 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature