Ontology highlight
ABSTRACT:
SUBMITTER: Ma M
PROVIDER: S-EPMC4845661 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Journal of natural products 20150903 10
Angucyclines and angucyclinones are aromatic polyketides with a tetracyclic benz[a]anthracene skeleton. The benz[a]anthracene scaffold is biosynthesized by type II polyketide synthases that catalyze the decarboxylative condensation of a short acyl-CoA starter and nine extender units. Angucyclines and angucyclinones, the largest group of polycyclic aromatic polyketides, achieve structural diversity via subsequent oxidation, ring cleavage, amino acid incorporation, and glycosylation. We here repor ...[more]